| Bruce Willis (Harry S. Stamper) | Billy Bob Thornton (Dan Truman, NASA Administrator) | Ben Affleck (A.J. Frost) |
| Liv Tyler (Grace Stamper) | Will Patton (Charles 'Chick' Chapple) | Steve Buscemi (Rockhound) |
| William Fichtner (Colonel William Sharp, Shuttle Freedom P) | Owen Wilson (Oscar Choi, Geologist) | Michael Clarke Duncan (Jayotis 'Bear' Kurleenbear) |
| Peter Stormare (Lev Andropov, Russian Cosmonaut) | Ken Hudson Campbell (Max Lennert) | Jessica Steen (Jennifer Watts, Shuttle Freedom Co-Pilot) |
| Keith David (Lt. General Kimsey) | Chris Ellis (Walter Clark) | Jason Isaacs (Dr. Ronald Quincy, Research) |
| Grayson McCouch (Gruber, Munitions Specialist) | Clark Heathcliffe Brolly (Freddy Noonan) | Marshall R. Teague (Colonel Davis, USAF (as Marshall Teague)) |
| Anthony Guidera (Tucker, Shuttle Independence Co-Pilot) | Greg Collins (Lt. Halsey, Munitions Specialist) | J. Patrick McCormack (General Boffer) |
| Ian Quinn (Astronaut Pete Shelby) | Christopher J. Worret (Operator #1) | Adam Smith (Operator #2) |
| John Mahon (Karl) | Grace Zabriskie (Dottie) | K.C. Leomiti (Samoan) |
| Eddie Griffin (Little Guy) | Deborah Nishimura (Client #1) | Albert Wong (Client #2) |
