| Clint Eastwood (Monco) | Lee Van Cleef (Col. Douglas Mortimer) | Gian Maria Volonté (El Indio) |
| Mara Krupp (Mary (as Mara Krup)) | Luigi Pistilli (Groggy) | Klaus Kinski (Wild (the hunchback)) |
| Joseph Egger (Old Prophet (as Josef Egger)) | Panos Papadopulos (Sancho Perez (as Panos Papadopoulos)) | Benito Stefanelli (Yuri) |
| Roberto Camardiel (Station clerk (as Robert Camardiel)) | Aldo Sambrell (Cuccillo) | Luis Rodríguez (Guy Calloway (as Luis Rodriguez)) |
| Tomas Blanco (Santa Cruz Telegrapher (as Tomas Blanco)) | Lorenzo Robledo (Tomaso) | Sergio Mendizabal (Tucumcari bank manager (as Sergio Mendiz) |
| Dante Maggio (Indio's Cell Mate) | Diana Rabito (Girl in tub) | Giovanni Tarallo (Bank Guard) |
| Mario Meniconi (Train Conductor) | Mario Brega (Nino) | Werner Abrolat (Slim, member of Indio's gang) |
| Roman Ariznavarreta (Shaved Bounty Hunter (non-crédité)) | Frank Brana (Blackie (non-crédité)) | Jose Canalejas (Chico (Indio gang member) (non-crédité)) |
| Rosemary Dexter (Mortimer's sister (non-crédité)) | Diana Faenza (Tomaso's wife (non-crédité)) | Eduardo García ((non-crédité)) |
| Jesús Guzman (Carpetbagger on Train (non-crédité)) | Peter Lee Lawrence (Mortimer's brother-in-law (non-crédité)) | Francesca Leone (Crying baby (non-crédité)) |
